TABLE 1.

Correlation between differentially expressed TFs and their target genes in common-stage1 and common-stage2.

Common-stage 1			Common-stage 2
Gene	Negative	Positive	Gene	Negative	Positive
Stat3	32	0	Stat3	0	52
Srf	0	24	Cebpb	0	45
Stat5a	23	0	Myod1	0	33
Klf2	0	22	Srf	32	1
Runx1	22	0	Ppargc1a	30	0
Ppargc1a	0	21	Nfe2l2	0	31
Cebpb	18	0	Runx1	0	31
Myod1	18	0	Atf3	0	23
Foxo4	0	16	Atf4	22	0
Nfe2l2	15	0	Junb	0	22
Atf4	0	12	Runx2	0	20
Egr1	11	0	Myf6	0	19
Junb	11	0	Klf2	19	0
Myf6	11	0	Egr1	0	17
Runx2	10	0	Sox9	0	17
Tead4	10	0	Stat5a	0	17
Atf6	8	0	Tead4	0	17
Klf5	8	0	Foxo4	8	0
Mef2a	6	0	Nr4a1	8	0
Atf3	5	0	Klf5	0	6
Nfix	1	2	Atf6	0	5
Nr4a1	0	3	Myog	0	5
Sox9	3	0	Nfix	3	1
Tcf12	3	0	Mef2a	0	3
Ppara	0	2	Sp1	0	2
Hes6	1	0	Tcf12	0	2
Lhx2	0	1	Tfe3	0	2
Myog	1	0	Hes6	0	1
Rest	1	0	Rest	0	1
Rxrg	0	1	Lhx2	1	0
Sp1	0	1	Ppara	1	0
Tfe3	1	0	Rxrg	1	0
			Scx	0	4
			Stat1	0	1
			Stat5b	0	1

Stage1- cc3, cc4 (DEGs were downregulation with time); stage2- cc1, cc2 (DEGs were upregulation with time).