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. 2022 Jun 24;13:897366. doi: 10.3389/fimmu.2022.897366

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Copyright © 2022 Li and Hua

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identifying distinct myeloid cell clusters in all samples. t-SNE projection of 10 subsets of myeloid cells (each dot corresponds to one single cell) shown in different colors (A). Proportions of all cell types clusters among four groups (B). Violin plots representing the distribution module score for selected genes for each cluster. Error bars indicated the means ± SD (C). Heatmap indicating the expression of selected gene sets in myeloid cell subtypes (D). Heatmap indicating the differentially expressed genes in seven macrophages subtypes (E). Violin plots showing the scores of functional modules for each macrophages cluster, using the AddModuleScore function. (**P < 0.01; ***P < 0.001) (F). NS, no significant.