TABLE 2.

Thirteen differentially expressed miRNAs observed upregulated in the PeCa patients, and their respective chromosomal location and HPV integration sites (presented by miRNA number).

miRNAs	Cytoband	Start—Stop (bp)	Integration site HPV (genotype) a	miRNA expression	Frequency (%)	Log2FC	p-Value	Adj.-p
let-7a-5p	9q22.32	96,938,234–96,938,325	yes, (16.18)	upregulated	100.0	2.2266	0.0019	0.0044
miR-130a-3p	11q12.1	57,641,198–57,641,286	yes, (16)	upregulated	100.0	1.1603	0.0008	0.0024
miR-142-3p	17q22	58,331,222–58,331,327	yes, (16)	upregulated	86.4	1.4576	0.0054	0.0089
miR-15b-5p	3q25.33	160,404,588–160,404,685	yes, (16)	upregulated	100.0	1.6509	0.0000	0.0006
miR-16-5p	13q14.2	50,623,109–50,623,197	yes, (16)	upregulated	95.5	1.2512	0.0008	0.0024
miR-200c-3p	12p13.31	6,963,694–6,963,771	no	upregulated	95.5	1.2541	0.0023	0.0049
miR-205-5p	1q32.2	209,428,820–209,432,384	yes, (16.18)	upregulated	95.5	1.4610	0.0013	0.0035
miR-21-5p	17q23.1	59,841,262–59,841,342	yes, (16.18)	upregulated	100.0	1.4629	0.0004	0.0016
miR-223-3p	Xq12	66,018,870–66,018,979	no	upregulated	95.5	2.0222	0.0028	0.0056
miR-22-3p	17p13.3	1,617,197–1,617,281	yes, (16)	upregulated	91.0	1.0605	0.0018	0.0043
miR-25-3p	7q22.1	100,093,560–100,093,643	yes, (16)	upregulated	100.0	1.5448	0.0001	0.0008
miR-31-5p	9p21.3	21,512,114–21,512,184	yes, (16)	upregulated	91.0	2.0012	0.0006	0.0020
miR-93-5p	7q22.1	99,691,391–99,691,470	yes, (16)	upregulated	95.5	1.0525	0.0016	0.0040

^aData obtained from HPVBase (Kumar Gupta and Kumar, 2015) and VISDB (Tang et al., 2020).