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. 2022 Mar 25;7(7):1493–1501. doi: 10.1016/j.ekir.2022.03.018

Figure 1.

Figure 1

Sampling of (a) MESA and (b) REGARDS cohorts per case-cohort design. (a) Among 6086 MESA participants, a total of 5137 had eGFR > 60 ml/min per 1.73 m2 and were nondiabetic at baseline, and a subcohort of 497 individuals was randomly selected from those participants. There were 163 cases of incident CKD, 18 of whom had also been selected into the subcohort and 145 cases arising outside the subcohort. (b) Among 13,071 REGARDS participants with 2 measures of serum creatinine, a total of 10,299 had eGFR > 60 ml/min per 1.73 m2 and were nondiabetic at baseline. A subcohort of 497 individuals was randomly selected from those participants. There were 497 cases of incident CKD, 57 of whom had also been selected into the subcohort and 440 cases arising outside the subcohort. CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; MESA, Multi-Ethnic Study of Atherosclerosis; REGARDS, Reasons for Geographic and Racial Differences in Stroke.