. 2022 Mar 25;7(7):1493–1501. doi: 10.1016/j.ekir.2022.03.018

Table 2.

Partial Pearson correlations evaluating associations of plasma biomarkers with each other and with eGFR and UACR in MESA and REGARDS

Plasma biomarkers	MESA								REGARDS
Plasma biomarkers	KIM-1	MCP-1	suPAR	TNFR-1	TNFR-2	YKL-40	UACR	eGFR	KIM-1	MCP-1	suPAR	TNFR-1	TNFR-2	YKL-40	UACR	eGFR
KIM-1	1.000	0.169^a	0.184^a	0.243^a	0.147^a	0.268^a	0.267^a	−0.157^a	1.000	0.154^a	0.234^a	0.272^a	0.163^a	0.217^a	0.150^a	–0.215^a
MCP-1		1.000	0.328^a	0.264^a	0.253^a	0.139^a	0.122^a	–0.084		1.000	0.356^a	0.330^a	0.332^a	0.189^a	0.107^a	–0.225^a
suPAR			1.000	0.603^a	0.547^a	0.285^a	0.090^a	–0.184^a			1.000	0.553^a	0.551^a	0.244^a	0.034	–0.261^a
TNFR-1				1.000	0.695^a	0.322^a	0.050	–0.394^a				1.000	0.778^a	0.262^a	–0.033	–0.482^a
TNFR-2					1.000	0.334^a	0.037	–0.268^a					1.000	0.298^a	–0.003	–0.449^a
YKL-40						1.000	0.157^a	–0.227^a						1.000	0.109^a	–0.222^a
UACR							1.000	–0.032							1.000	0.031
eGFR								1.000								1.000

eGFR, estimated glomerular filtration rate; KIM-1, kidney injury molecule 1; MCP-1, monocyte chemotactic protein-1; MESA, Multi-Ethnic Study of Atherosclerosis; REGARDS, Reasons for Geographic and Racial Differences in Stroke; suPAR, soluble urokinase-type plasminogen activator receptor; TNFR, tumor necrosis factor receptor; YKL-40, chitinase 3-like protein 1; UACR, urine albumin-to-creatinine ratio.

All analyses are adjusted for age and sex.

P < 0.05.