Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 10;30(7):2603–2617. doi: 10.1016/j.ymthe.2022.03.003

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The American Society of Gene and Cell Therapy.

PMC Copyright notice

PRMT5 positively correlates with nuclear ALKBH5 and predicts relatively poor survival in breast cancer patients

(A) The relationship between PRMT5 expression and human breast cancer patient survival in TCGA datasets was analyzed. (B) The relationship between BRCA1 expression and human breast cancer patient survival in TCGA datasets was analyzed. (C) The relationship between PRMT5 and BRCA1 gene expression in breast cancer patients was analyzed, and the correlation coefficient R was calculated by the Pearson method. (D) The relationship between PRMT5 and BRCA1 protein expression in breast cancer patients was analyzed, and the correlation coefficient R was calculated by the Pearson method. (E) The relationship between PRMT5 and ALKBH5 nuclear expression in breast cancer patients was analyzed. (F) The relationship between PRMT5 and ALKBH7 protein expression in breast cancer patients was analyzed. (G) Accumulated nuclear ALKBH5, BRCA1, and ALKBH7 proteins were observed in human breast cancer tissue with high PRMT5 expression by IHC compared with breast cancer tissue with low PRMT5 expression.