TABLE 2.

Microfluidic devices providers with the different materials used for manufacturing.

Companies	Devices		Applications
	Architecture	Materials
AIM Biotech	3 compartments	TP	Gel compatible devices for co-culture models (cell invasion and migration, vascular functions…). BBB model
Ananda	2 compartments with microchannels	PDMS	Co-culture, high-throughput assays
AxoSim	1 and 2 compartments	PEG	Nerve on a chip model Mini-brain organoid
Emulate	2 and 3 compartments with membrane	PDMS, membrane	Co-culture neurons-endothelial cells
MicroBrainTech	2 and 3 compartments with microchannels and axonal diodes	PDMS	Axonal directionality for unidirectional neuronal network models
Mimetas	2 and 3 compartments with gel interface	PS and glass	Hydrogel compatible for ECM models
NETRI	1 to 5 compartments with/without microchannels or membrane	PDMS, PS, membrane	Co-culture, NDD models, Network architectures, Interface models, high-throughput assays
SynVivo	3 compartments with membrane	PDMS, membrane	BBB model
Xona	2 and 3 compartments with microchannels	COC and silicone	Axonal isolation

COC, Cyclic olefin copolymer; PDMS, Polydimethylsiloxane; PED, polyethylene glycol; PS, Polystyren; TP, Thermoplastic.