TABLE 1.
Top 10 up-regulation differentially expressed genes in MN group.
| Rank | Gene symbol | Gene description | logFC | Adj.p.val |
|---|---|---|---|---|
| 1 | ECM1 | Extracellular matrix protein 1; interacts with a variety of extracellular and structural proteins | 2.99 | <0.001 |
| 2 | COLEC12 | Collectin subfamily member 12; a member of the C-lectin family, proteins that possess collagen-like sequences | 2.79 | <0.001 |
| 3 | FCER1G | Fc fragment of IgE receptor Ig; involved in allergic reactions | 2.53 | <0.001 |
| 4 | MYOZ2 | Myozenin 2; a member of sarcomeric proteins that bind to calcineurin | 2.42 | <0.001 |
| 5 | CHGA | Chromogranin A; a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins | 2.39 | <0.001 |
| 6 | TGFBI | Transforming growth factor beta induced; encodes an RGD-containing protein that binds to type I, II and IV collagens | 2.34 | <0.001 |
| 7 | HBB | Hemoglobin subunit beta; a type of polypeptide chains in adult hemoglobin | 2.33 | <0.001 |
| 8 | TNFRSF12A | TNF receptor superfamily member 12A; contributes to endothelial dysfunction | 2.30 | <0.001 |
| 9 | BMP2 | Bone morphogenetic protein 2; encodes a secreted ligand of the transforming growth factor-beta superfamily of proteins | 2.25 | <0.001 |
| 10 | LYZ | Lysozyme; encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan | 2.16 | <0.001 |