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. 2022 Jun 24;13:914382. doi: 10.3389/fphys.2022.914382

TABLE 2.

Top 10 down-regulation differentially expressed genes in MN group.

Rank Gene symbol Gene description logFC Adj.p.val
1 G6PC Glucose-6-phosphatase; a multisubunit integral membrane protein of the endoplasmic reticulum −2.49 <0.001
2 CALB1 Calbindin 1; a member of the calcium-binding protein superfamily that includes calmodulin and troponin C −2.37 <0.001
3 SLC22A8 Solute carrier family 22 member 8; involved in the excretion of some toxic organic anions −2.32 <0.001
4 ALB Albumin; encodes the most abundant protein in human blood −2.31 <0.001
5 AFM Afamin; a member of the albumin gene family −2.29 <0.001
6 PCK1 Phosphoenolpyruvate carboxykinase 1; a main control point for the regulation of gluconeogenesis −2.20 <0.001
7 CYP2B6 Cytochrome P450 family 2 subfamily B member 6; a member of the cytochrome P450 superfamily of enzymes −2.18 <0.001
8 PLG Plasminogen; plays a role in the degradation of extracellular matrices, cell migration, inflammation −2.06 <0.001
9 CYP27B1 Cytochrome P450 family 27 subfamily B member 1; a member of the cytochrome P450 superfamily of enzymes −2.05 <0.001
10 SLC27A2 Solute carrier family 27 member 2; play a key role in lipid biosynthesis and fatty acid degradation −2.02 <0.001