TABLE 2.
Top 10 down-regulation differentially expressed genes in MN group.
Rank | Gene symbol | Gene description | logFC | Adj.p.val |
---|---|---|---|---|
1 | G6PC | Glucose-6-phosphatase; a multisubunit integral membrane protein of the endoplasmic reticulum | −2.49 | <0.001 |
2 | CALB1 | Calbindin 1; a member of the calcium-binding protein superfamily that includes calmodulin and troponin C | −2.37 | <0.001 |
3 | SLC22A8 | Solute carrier family 22 member 8; involved in the excretion of some toxic organic anions | −2.32 | <0.001 |
4 | ALB | Albumin; encodes the most abundant protein in human blood | −2.31 | <0.001 |
5 | AFM | Afamin; a member of the albumin gene family | −2.29 | <0.001 |
6 | PCK1 | Phosphoenolpyruvate carboxykinase 1; a main control point for the regulation of gluconeogenesis | −2.20 | <0.001 |
7 | CYP2B6 | Cytochrome P450 family 2 subfamily B member 6; a member of the cytochrome P450 superfamily of enzymes | −2.18 | <0.001 |
8 | PLG | Plasminogen; plays a role in the degradation of extracellular matrices, cell migration, inflammation | −2.06 | <0.001 |
9 | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; a member of the cytochrome P450 superfamily of enzymes | −2.05 | <0.001 |
10 | SLC27A2 | Solute carrier family 27 member 2; play a key role in lipid biosynthesis and fatty acid degradation | −2.02 | <0.001 |