Table 3.
Multivariate regression linear analysis between neuropsychological test in CSVD and vascular risks.
| B (95%CI) | P | VIF | |
|---|---|---|---|
| MoCA | |||
| ALPS-index | 16.094 (5.064 to 27.123) | 0.005 | 1.290 |
| Age | 0.094 (−0.089 to 0.277) | 0.310 | 1.156 |
| Education | 0.683 (0.398 to 0.968) | <0.001 | 1.042 |
| Hypertension | −1.808 (−5.505 to 1.889) | 0.334 | 1.211 |
| Diabetes | −0.292 (−3.483 to 2.899) | 0.856 | 1.100 |
| Smoking | 0.793 (−3.186 to 4.771) | 0.693 | 1.593 |
| Alcohol abuse | −0.254 (−5.250 to 4.742) | 0.920 | 1.650 |
| TMT(B-A) | |||
| ALPS-index | −252.082 (−441.516 to −62.647) | 0.010 | 1.266 |
| Age | 1.921 (−1.629 to 5.472) | 0.285 | 1.186 |
| Education | −7.156 (−13.146 to −1.167) | 0.020 | 1.066 |
| Hypertension | 62.526 (1.247 to 123.805) | 0.046 | 1.208 |
| Diabetes | 0.268 (−61.498 to 62.035) | 0.993 | 1.101 |
| Smoking | −26.107 (−99.679 to 47.465) | 0.483 | 1.498 |
| Alcohol abuse | 137.343 (42.367 to 232.318) | 0.005 | 1.524 |
| AVLT-sum | |||
| ALPS-index | 25.914 (9.687 to 42.140) | 0.002 | 1.283 |
| Age | 0.160 (−0.135 to 0.455) | 0.284 | 1.174 |
| Education | 0.603 (0.104 to 1.101) | 0.018 | 1.079 |
| Hypertension | −5.964 (−11.233 to −0.696) | 0.027 | 1.201 |
| Diabetes | 0.867 (−4.204 to 5.938) | 0.735 | 1.113 |
| Smoking | −3.089 (−9.421 to 3.243) | 0.335 | 1.551 |
| Alcohol abuse | −2.662 (−10.777 to 5.453) | 0.517 | 1.609 |
| SDMT | |||
| ALPS-index | 43.740 (21.540 to 65.939) | <0.001 | 1.372 |
| Age | −0.091 (−0.459 to 0.278) | 0.627 | 1.216 |
| Education | 1.203 (0.586 to 1.820) | <0.001 | 1.057 |
| Hypertension | −8.334 (−16.278 to −0.390) | 0.040 | 1.238 |
| Diabetes | −2.977 (−9.205 to 3.250) | 0.344 | 1.103 |
| Smoking | 0.609 (−6.959 to 8.176) | 0.873 | 1.456 |
| Alcohol abuse | −4.824 (−14.795 to 5.147) | 0.339 | 1.558 |
| VFT | |||
| ALPS-index | 27.108 (7.411 to 46.804) | 0.008 | 1.359 |
| Age | 0.006 (−0.319 to 0.331) | 0.971 | 1.201 |
| Education | 0.672 (0.132 to 1.212) | 0.015 | 1.098 |
| Hypertension | −9.226 (−15.919 to −2.532) | 0.008 | 1.166 |
| Diabetes | −2.916 (−8.175 to 2.343) | 0.273 | 1.109 |
| Smoking | −1.928 (−8.280 to 4.424) | 0.547 | 1.508 |
| Alcohol abuse | −5.996 (−14.165 to 2.173) | 0.148 | 1.614 |
| BNT | |||
| ALPS-index | 0.975 (−7.223 to 9.173) | 0.814 | 1.344 |
| Age | 0.003 (−0.136 to 0.142) | 0.969 | 1.229 |
| Education | 0.578 (0.358 to 0.798) | <0.001 | 1.045 |
| Hypertension | −0.068 (−2.906 to 2.770) | 0.962 | 1.205 |
| Diabetes | −0.644 (−2.967 to 1.679) | 0.583 | 1.104 |
| Smoking | 0.078 (−2.746 to 2.902) | 0.956 | 1.517 |
| Alcohol abuse | 1.526 (−2.102 to 5.154) | 0.405 | 1.606 |
| RCFT-C | |||
| ALPS-index | 5.153 (−10.967 to 21.274) | 0.526 | 1.266 |
| Age | −0.187 (−0.465 to 0.092) | 0.186 | 1.181 |
| Education | 0.580 (0.140 to 1.019) | 0.010 | 1.046 |
| Hypertension | −2.081 (−7.841 to 3.678) | 0.474 | 1.177 |
| Diabetes | 0.177 (−4.451 to 4.806) | 0.939 | 1.090 |
| Smoking | −0.255 (−5.892 to 5.382) | 0.928 | 1.489 |
| Alcohol abuse | −1.431 (−8.589 to 5.727) | 0.692 | 1.556 |
ALPS-index, diffusion tensor image analysis along the perivascular space; MoCA, Montreal Cognitive Assessment; AVLT-sum, total number of five times recall of three trial Auditory Verbal Learning Test; TMT (B-A), time of Trail Making Test B- time of Trail Making Test A; VFT, Category Verbal Fluency Test; SDMT, Symbol Digit Modalities Test; RCFT-C, Rey's Complex Figure Test copy trail; BNT, Boston Naming Test.