Table 3.
Multiple regression analysis with ERI (natural log) as the dependent variable
| Model 1 | β | 95% CI | P value |
|---|---|---|---|
| Female (vs. male) | 0.60 | 0.30–0.91 | <0.001 |
| Age, yrs | 0.008 | −0.002 to 0.018 | 0.13 |
| Time on dialysis (≥49 mo) (vs. <49 mo) | 0.35 | 0.09–0.61 | 0.008 |
| Selenium, μg/dl | −0.12 | −0.16 to −0.07 | <0.001 |
| TSAT, % (natural log) | −0.52 | −0.76 to −0.29 | <0.001 |
| Model 2 | b | 95% CI | P value |
|---|---|---|---|
| Female (vs. male) | 0.59 | 0.27–0.91 | <0.001 |
| Age, years | 0.01 | −0.01 to 0.02 | 0.34 |
| Time on dialysis (≥49 mo) (vs. <49 mo) | 0.33 | 0.07–0.60 | 0.02 |
| Selenium, μg/dl | −0.11 | −0.15 to −0.06 | <0.001 |
| TSAT, % (natural log) | −0.47 | −0.77 to −0.18 | 0.002 |
| Ferritin, ng/ml (natural log) | −0.07 | −0.23 to 0.09 | 0.38 |
| Cardiovascular diseases | −0.04 | −0.17 to 0.10 | 0.59 |
| Alb, g/dl | −0.36 | −0.77 to 0.04 | 0.08 |
| CRP, mg/dl (natural log) | −0.03 | −0.14 to 0.07 | 0.55 |
| Model 3 | b | 95% CI | P value |
|---|---|---|---|
| Female (vs. male) | 0.56 | 0.21–0.91 | 0.002 |
| Age, yrs | 0.00 | −0.01 to 0.02 | 0.43 |
| Time on dialysis (≥49 mo) (vs. <49 mo) | 0.29 | −0.01 to 0.60 | 0.06 |
| Selenium, μg/dl | −0.11 | −0.15 to −0.06 | <0.001 |
| TSAT, % (natural log) | −0.47 | −0.77 to −0.18 | 0.002 |
| Ferritin, ng/ml (natural log) | −0.07 | −0.23 to 0.10 | 0.43 |
| Cardiovascular diseases | −0.05 | −0.19 to 0.09 | 0.49 |
| Alb, g/dl | −0.34 | −0.77 to 0.10 | 0.13 |
| CRP, mg/dl (natural log) | −0.02 | −0.13 to 0.09 | 0.66 |
| iPTH, pg/ml (natural log) | 0.12 | −0.10 to 0.34 | 0.28 |
| Zinc, μg/dl | 0.00 | −0.01 to 0.01 | 0.95 |
| HDF (vs. HD) | 0.04 | −0.29 to 0.37 | 0.82 |
| spKt/V | 0.21 | −0.50 to 0.92 | 0.56 |
Alb, albumin; CRP, C-reactive protein; ERI, erythropoiesis resistance index; HD, hemodialysis; HDF, hemodiafiltration; iPTH, intact parathyroid hormone; spKt/V, single-pool Kt/V; TSAT, transferrin saturation.