Table 3.
Comparison of distribution of mortality between the 2 phases
| Microorganism | Phase I (1998–2007) | Phase II (2008–2017) | P value | OR (95% CI) |
|---|---|---|---|---|
| Mortality | 39/315 | 27/426 | ||
| Klebsiella pneumoniae | 5/33 (15.2) | 7/31 (22.6) | 0.447a) | 1.633 (0.458–5.819) |
| ESBL-producing | 2/5 (40.0) | 5/7 (71.4) | ||
| Pseudomonas aeruginosa | 7/20 (35.0) | 2/3 (66.7) | 0.538b) | 3.714 (0.284–48.545) |
| Staphylococcus aureus | 6/55 (10.9) | 3/57 (5.3) | 0.317b) | 0.454 (0.108–1.913) |
| Staphylococcus epidermidis | 5/122 (5.0) | 3/125 (1.2) | 0.047b) | 0.234 (0.055–0.997) |
| Escherichia coli | 4/14 (28.6) | 2/14 (14.3) | 0.648b) | 0.417 (0.063–2.768) |
| Enterobacter cloacae | 3/22 (13.6) | 1/10 (10.0) | 1.000b) | 0.704 (0.064–7.742) |
| Mortality of EOS | 7/33 (21.2) | 5/17 (29.4) | 0.728b) | 1.548 (0.407–5.887) |
| Mortality of LOS | 32/282 (11.3) | 22/409 (5.4) | 0.004a) | 0.444 (0.252–0.782) |
| Total mortality | 39/315 (12.4) | 27/426 (6.3) | 0.004a) | 0.479 (0.286–0.801) |
Values are presented as number (%).
OR, odds ratio; CI, confidence interval; ESBL, extended spectrum β-lactamases; EOS, early-onset sepsis; LOS, late-onset sepsis.
a)
Chi-square test.
b)
Fisher extract test.
Boldface indicates a statistically significant difference with P<0.05.