TABLE 1.
Male phenotypes.
| Phenotype | LH male (n = 29) | LH17LNa male (n = 30) | p-value |
|---|---|---|---|
| Body mass | |||
| Body mass (g) at 8 weeks | 252.8 ± 1.494 | 247.6 ± 2.805 | 0.1071# |
| Body mass (g) at 11 weeks | 333.8 ± 1.719 | 327.3 ± 2.848 | 0.0568# |
| Body mass (g) at 14 weeks | 385.2 ± 2.248 | 376.9 ± 3.047 | 0.0332* |
| Body composition | |||
| Body Fat % at 8 weeks | 6.600 ± 0.255 | 7.352 ± 0.242 | 0.0364* |
| Fat mass (g) at 8 weeks | 16.80 ± 0.679 | 18.40 ± 0.706 | 0.1079* |
| Fat Free mass (g) at 8 weeks | 237.2 ± 1.483 | 231.1 ± 2.825 | 0.0638# |
| Body Fat % at 11 weeks | 8.367 ± 0.279 | 8.736 ± 0.260, n = 26 | 0.341* |
| Fat mass (g) at 11 weeks | 27.96 ± 0.953 | 28.58 ± 0.960, n = 26 | 0.6518* |
| Fat Free mass (g) at 11 weeks | 306.1 ± 1.733 | 297.9 ± 2.580, n = 26 | 0.010* |
| Body Fat % at 14 weeks | 10.11 ± 0.277 | 9.821 ± 0.304 | 0.4934* |
| Fat mass (g) at 14 weeks | 38.99 ± 1.085 | 37.12 ± 1.284 | 0.273* |
| Fat Free mass (g) at 14 weeks | 346.8 ± 2.214 | 340.3 ± 2.599 | 0.0604* |
| Organ masses | |||
| Left ventricle mass (g) | 1.004 ± 0.010 | 0.964 ± 0.011 | 0.0111* |
| Adjusted left ventricle mass (mg/g) | 2.610 ± 0.024 | 2.551 ± 0.022 | 0.0811* |
| Total kidney mass (g) | 2.144 ± 0.027 | 2.021 ± 0.022 | 0.0014 $ |
| Adjusted total kidney mass (mg/g) | 5.572 ± 0.059 | 5.349 ± 0.037 | 0.0021 $ |
| Thymus gland mass (mg) | 481.7 ± 0.014, n = 8 | 442.1 ± 0.008, n = 11 | 0.0163* |
| Adjusted thymus gland mass (mg/g) | 1.258 ± 0.031, n = 8 | 1.147 ± 0.021, n = 11 | 0.0067* |
| Metabolic phenotypes | |||
| Average heat production (kcal/h) | 2.299 ± 0.0242, n = 15 | 2.186 ± 0.0413, n = 10 | 0.019 * |
| FFM-adjusted Sleep Metabolic rate (kcal/h) | 2.079 ± 0.046, n = 15 | 1.994 ± 0.057, n = 10 | 0.271 GLM (FFM = 293.9) |
| Total meters/48 h | 110.0 ± 21.65, n = 12 | 232.2 ± 61.33, n = 8 | 0.0938# |
| Food intake (g)/48 h | 41.83 ± 0.712, n = 15 | 38.19 ± 0.525, n = 10 | 0.0011* |
| Feeding event counts/48hr | 89.93 ± 3.208, n = 15 | 90.70 ± 3.229, n = 10 | 0.8729* |
| Meal size (g/feeding event) | 0.531 ± 0.0197, n = 15 | 0.477 ± 0.0178, n = 10 | 0.0545$ |
| Feeding event duration (min) | 3.029 ± 0.081, n = 15 | 3.113 ± 0.158, n = 10 | 0.6088* |
| Meal eating speed (food g/min) | 0.109 ± 0.005, n = 15 | 0.108 ± 0.009, n = 10 | 0.683$ |
| Inter-meal interval (min) | 34.52 ± 1.44, n = 15 | 33.37 ± 1.08, n = 10 | 0.566* |
*via Unpaired two-tailed t-test; #via Welch’s unpaired two-tailed t-test; $via Mann-Whitney, significant values are bolded.