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. 2022 Jun 24;13:903971. doi: 10.3389/fgene.2022.903971

TABLE 2.

Genes and variant positions within coding exons.

Annotation impact Gene symbol Gene name Variant position (mRatBN7.2) Amino acid change Provean prediction Variant strain
High Ercc6l2 ERCC excision repair 6 like 2 chr17:1282819 p.Cys419fs DELETERIOUS LN
−15.98
Moderate C17h6orf52 Similar to human chromosome 5 open reading frame 52 NEUTRAL LH
chr17:23762853 p.Val103Ile −0.055
chr17:23771379 p.Arg202His −0.040
chr17:23771391 p.Cys206Tyr −0.572
Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) chr17:23900685 p.Ala131Thr NEUTRAL LN
1.544
Ofcc1 Orofacial cleft candidate 1 chr17:24797711 pThr845Ile DELETERIOUS LN
−3.767

Note: PROVEAN scores < −2.5 were considered deleterious by the prediction tool.