Table 2.
Comparison of biochemical indexes between control and NASH mice.
| Variables | Control group | NASH group | Change trend |
|---|---|---|---|
| ALT (U/L) | 303.624 ± 156.477 | 405.847 ± 132.862 | − |
| DBIL (μmol/L) | 17.134 ± 3.128 | 25.320 ± 4.083*** | ↑ |
| TBIL (μmol/L) | 25.092 ± 5.175 | 41.306 ± 4.649*** | ↑ |
| ALB (g/L) | 38.330 ± 4.513 | 49.912 ± 2.199*** | ↑ |
| ALP (U/L) | 103.984 ± 10.823 | 171.207 ± 26.146*** | ↑ |
| γ-GT (U/L) | 4.849 ± 4.063 | 10.108 ± 2.220** | ↑ |
| TG (mmol/L) | 1.761 ± 0.307 | 2.445 ± 0.373** | ↑ |
| TC (mmol/L) | 3.727 ± 0.395 | 3.345 ± 0.354 | − |
| HDL-c (mmol/L) | 0.449 ± 0.137 | 0.775 ± 0.214** | ↑ |
| LDL-c (mmol/L) | 1.497 ± 0.270 | 1.092 ± 0.282* | ↓ |
| MDA (μmol/g) | 6.906 ± 1.964 | 9.938 ± 4.057 | − |
Note: ALT: alanine transaminase; DBIL: direct bilirubin; TBIL: total bilirubin; ALB: albumin; ALP: alkaline phosphatase; γ-GT: gamma-glutamyl transpeptidase; TG: triglyceride; TC: total cholesterol; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; MDA: malondialdehyde. Data are mean ± SD, n = 8; *p < 0.05, **p < 0.01, ***p < 0.001 versus control group. −: not significant. ↑: significantly increased. ↓: significantly decreased.