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. 2021 Nov 17;39:203–223. doi: 10.1016/j.jare.2021.11.005

Fig. 1.

Fig. 1

Characterization of exosomes derived from the serum of healthy volunteers and septic patients. (A) The typical morphological characteristics of isolated exosomes were detected by TEM. (B) The size distribution of serum exosomes was determined by NTA. (C) Molecular markers for exosomes (Alix and CD63) were detected by Western blot analysis. (D) PCA of serum-derived exosomes from healthy volunteers and septic patients. (E) GO enrichment analysis was performed with cellular component terms to further confirm the quality and purity of the serum-derived exosome samples. (F) Overview of the experimental design for multiomics analysis of serum exosomes derived from septic patients.