Table 2. Summary of the major developments regarding the role of NLRP3 inflammasome in acne vulgaris.

Items	References
NLRP3 inflammasome participates in the pathogenesis of acne vulgaris	(18,19,21,23-25,37)
NLRP3 inflammasome is a potential therapeutic target for acne vulgaris	(8,16,18,19,21,25,35-37)
A variety of innate immune pathways are involved in the pathogenesis of acne vulgaris	(15,39,40,42-50,52)
Adaptive immune responses in the development of acne vulgaris	(14,55-61)

NLRP3, nucleotide oligomerization domain-like receptor family pyrin containing 3.