Figure 3.

Differentiation kinetics of SARS-CoV-2 S₂₆₉ MHC-I multimer⁺CD8⁺ T cells in BNT162b2-vaccinated individuals

(A) The percentages indicate subpopulations among SARS-CoV-2-specific S₂₆₉ multimer⁺ memory CD8⁺ T cells in vaccinated individuals over time summarized in box graphs (n = 12).

(B) Correlation between the percentage of the indicated subpopulations of SARS-CoV-2-specific S₂₆₉ multimer⁺ memory CD8⁺ T cells and days post-second vaccination (n = 12) with black lines representing linear regression. Data are presented as median and IQR. Statistical analysis was performed using Mann-Whitney U test (A) or Spearman correlation test with linear regression analysis (B) (^∗∗p < 0.01, ^∗∗∗p < 0.001, ^∗∗∗∗p < 0.0001). See also Figure S4.