Figure 1.
Two-stage workflow. (A) Association of sNfL with neuropsychological test performances. (B) Combinations of sNfL and imaging markers for the prediction of SDMT performance using a support vector regression approach. sNfL = serum neurofilament light chain; SDMT = Symbol Digits Modalities Test; PASAT = Paced Auditory Serial Addition Test; VLMT = verbal learning and memory test; HADS-A = Hospital Anxiety and Depression Scale (Anxiety); HADS-D = Hospital Anxiety and Depression Scale (Depression); FSMC = Fatigue Scale for Motor and Cognitive functions; LV = lesion volume; GMV = grey matter volume.
