Table III.

Univariable and multivariable analysis for factors associated with liver metastases or death stratified for pNETs <2 and ≥2 cm

	Characteristic	No of patients	LM/death	Univariable analysis (crude HR)		Multivariable analysis (adjusted HR)
				HR	95% CI	HR	95% CI
pNET <2 cm	Age at surgery (per y)	60	9	1.03	0.98–1.08	1.03	0.98–1.08
	Tumor functionality
	Insulinoma	38	3	1	Ref cat	1	Ref cat
	NF-pNET	22	6	2.44	0.58–10.30	2.19	0.52–9.28
pNET ≥2 cm	Age at surgery (per y)	93	28	1.02	0.99–1.06	1.01	0.98–1.05
	Tumor functionality
	Insulinoma	54	12	1	Ref cat	1	Ref cat
	NF-pNET	39	16	3.11	1.39–6.98	2.92	1.28–6.67
	WHO grade
	G1	64	15	1	Ref cat	1	Ref cat
	G2/G3	29	13	2.13	0.998–4.55	2.52	1.16– 5.47

Data reported after multiple imputation.

Multivariable analysis includes age and tumor functionality; for pNETs ≥2 cm, WHO grade was additionally included. cat, category; Ref, reference.