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. 2022 Jun 24;9:912454. doi: 10.3389/fcvm.2022.912454

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Copyright © 2022 Han, Duan, Wu, Zheng, Gu, Cai, Lu, Wu, Li and Gu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Short Time-Series Expression Miner (STEM) analysis of gene expression profile. Squares of the same color indicate that the correlation is >0.7. (A) Trend analysis of genes. Gene expression was normalized in the STEM software and genes with maximal values minus minimal values not <1 were included in the analysis. The 7581 genes from 0, 1, and 72 h after MI were clustered into 8 profiles. (B,C) Significantly enriched trend analysis of profile#3, profile#4, and profile#7.