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. 2022 Jun 30;16:100347. doi: 10.1016/j.mtbio.2022.100347

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 9 — In vivo wound-healing study using a Wistar rat model of excisional wound-healing. (A) Representative macroscopic images of the wound without treatment (untreated), treatment with a flat composite scaffold, structural composite scaffold and structural composite scaffold loaded with gentamicin at 0, 3, 6-, 9-, 12- and 15-days of healing. Scale bar = 10 mm. (B) The respective wound traces indicate the healing status during the 15 days of the experiment. Quantitative analysis of (C) wound area and (D) wound-healing percentage as a function of time and treatments. The results are presented as means ± SD, n = 6. (∗p < 0.05; ∗∗p < 0.01 using one-way ANOVA followed by Tukey's post hoc test).