Table 4. Survival analysis by co-occurring mutations using TCGA data for lung adenocarcinoma (all stages).

Co-mutation	Univariable				Multivariable*
	HR	95% CI	P		HR	95% CI	P
STK11 wild type	Reference	Reference			Reference	Reference
STK11 mutated	2.50	1.00–6.21	0.049		3.36	1.23–9.21	0.018
STK11/KRAS co-mutated	2.43	1.09–5.42	0.030		3.37	1.33–8.49	0.010
STK11/TP53 co-mutated	1.39	0.53–3.63	0.499		1.79	0.59–5.41	0.303

*, adjusted for age, gender, race, stage and smoking status. TCGA, The Cancer Genome Atlas; HR, hazard ratio; CI, confidence interval.