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| On target |
| EGFR mutations: C797S, L718Q, G724S, C79X, L792X, G769X, S768I, G724S, G796S, V834L exon 20 insertion |
| EGFR amplification |
| Off target |
| MET amplification |
| HER2 mutation/amplification |
| PIK3CA mutation/amplification |
| KRAS mutation/amplification |
| PTEN mutation |
| Cell cycle gene alterations: CCND1, CCND2, CDKN2A, CDK6, CCNE1 |
| Small cell transformation |
| Squamous translocation |
EGFR, epidermal growth factor receptor.
