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. 2022 Jun;14(6):2131–2146. doi: 10.21037/jtd-22-494

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2022 Journal of Thoracic Disease. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Differential expression analysis in LUAD patients. (A) Heatmap illustrating all DEGs between 535 tumor samples (red) and 59 normal samples (blue). (B) Venn diagram illustrating 681 immune-related DEGs obtained by the intersection of 8,108 DEGs and 3,177 immune genes. (C) GO enrichment analysis of the immune-related DEGs. (D) KEGG pathway analysis of the immune-related DEGs. DEGs, differentially expressed genes; FC, fold change; GO, Gene Ontology; IL-17, interleukin-17; LUAD, lung adenocarcinoma; KEGG, Kyoto Encyclopedia of Genes and Genomes.