Table 5. VATS vs. RATS serum cytokine levels 24 hours post-operatively.
Cytokine | VATS median | RATS median | VATS mean |
RATS mean | Mean difference 24 hours | Mean difference 95% CI | Adjusted P value | VATS SEM | RATS SEM |
---|---|---|---|---|---|---|---|---|---|
IL-2 | 0.84 | 0.81 | 1.029 | 0.905 | 0.124 | −22.78 to 23.03 | 0.358 | 0.162 | 0.046 |
IL-4 | 1.45 | 1.55 | 1.478 | 1.502 | −0.024 | −22.93 to 22.88 | 0.08 | 0.077 | 0.012 |
IL-6 | 44.96 | 38.33 | 39.97 | 45.89 | −5.921 | −28.83 to 16.99 | 7.094 | 6.574 | 1.038 |
IL-8 | 6.64 | 4.52 | 13.220 | 5.724 | 7.498 | −15.41 to 30.40 | 4.732 | 0.683 | 0.577 |
IL-10 | 0.78 | 0.78 | 0.901 | 1.049 | −0.147 | −23.05 to 22.76 | 0.157 | 0.165 | 0.024 |
VEGF | 17.47 | 12.33 | 19.61 | 15.89 | 3.72 | −19.19 to 26.63 | 3.596 | 3.265 | 0.523 |
IFNG | 0.18 | 0.23 | 0.139 | 0.325 | −0.185 | −23.09 to 22.72 | 0.041 | 0.081 | 0.009 |
TNFA | 1.44 | 1.41 | 1.659 | 1.37 | 0.289 | −22.62 to 23.20 | 0.2 | 0.136 | 0.027 |
IL-1A | 0.11 | 0.12 | 0.116 | 0.273 | −0.157 | −23.06 to 22.75 | 0.035 | 0.149 | 0.014 |
IL-1B | 1.00 | 1.81 | 2.83 | 7.894 | −5.064 | −27.97 to 17.84 | 1.826 | 2.53 | 0.315 |
MCP-1 | 164.29 | 131.83 | 169.8 | 136.9 | 32.97 | 10.06 to 55.88 | 18.21 | 14.2 | 2.54 |
EGF | 1.23 | 2.35 | 1.556 | 4.643 | −3.087 | −25.99 to 19.82 | 0.338 | 1.188 | 0.113 |
VATS, video-assisted thoracic surgery; RATS, robotic-assisted thoracic surgery; CI, confidence interval; SEM, standard error of the mean; IL, interleukin; VEGF, vascular endothelial growth factor; IFNG, interferon-γ; TNFA, tumor necrosis factor-α; MCP-1, monocyte chemo-attractant protein-1; EGF, endothelial growth factor.