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. 2022 Jun;14(6):2000–2010. doi: 10.21037/jtd-21-1820

Table 5. VATS vs. RATS serum cytokine levels 24 hours post-operatively.

Cytokine VATS median RATS median VATS
mean
RATS mean Mean difference 24 hours Mean difference 95% CI Adjusted P value VATS SEM RATS SEM
IL-2 0.84 0.81 1.029 0.905 0.124 −22.78 to 23.03 0.358 0.162 0.046
IL-4 1.45 1.55 1.478 1.502 −0.024 −22.93 to 22.88 0.08 0.077 0.012
IL-6 44.96 38.33 39.97 45.89 −5.921 −28.83 to 16.99 7.094 6.574 1.038
IL-8 6.64 4.52 13.220 5.724 7.498 −15.41 to 30.40 4.732 0.683 0.577
IL-10 0.78 0.78 0.901 1.049 −0.147 −23.05 to 22.76 0.157 0.165 0.024
VEGF 17.47 12.33 19.61 15.89 3.72 −19.19 to 26.63 3.596 3.265 0.523
IFNG 0.18 0.23 0.139 0.325 −0.185 −23.09 to 22.72 0.041 0.081 0.009
TNFA 1.44 1.41 1.659 1.37 0.289 −22.62 to 23.20 0.2 0.136 0.027
IL-1A 0.11 0.12 0.116 0.273 −0.157 −23.06 to 22.75 0.035 0.149 0.014
IL-1B 1.00 1.81 2.83 7.894 −5.064 −27.97 to 17.84 1.826 2.53 0.315
MCP-1 164.29 131.83 169.8 136.9 32.97 10.06 to 55.88 18.21 14.2 2.54
EGF 1.23 2.35 1.556 4.643 −3.087 −25.99 to 19.82 0.338 1.188 0.113

VATS, video-assisted thoracic surgery; RATS, robotic-assisted thoracic surgery; CI, confidence interval; SEM, standard error of the mean; IL, interleukin; VEGF, vascular endothelial growth factor; IFNG, interferon-γ; TNFA, tumor necrosis factor-α; MCP-1, monocyte chemo-attractant protein-1; EGF, endothelial growth factor.