Table 3. Key takeaway points in older patients.

• NRCs indicate worse OS/LCSS after segmentectomy/wedge vs. lobectomy

• Marginal benefits in short-term outcomes for segmentectomy/wedge vs. lobectomy

• SBRT/ablation results in short-term benefits and long-term downsides vs. surgery

• Increasing age/frailty accentuates short-term benefits and diminishes long-term downsides of SBRT/ablation vs. surgery

• Selection criteria are not well-defined; factors affecting 90-day outcomes, technical success and tumor aggressiveness are probably most useful

• Patient preferences affect how outcomes are weighed

NRCs, non-randomized comparisons; OS, overall survival; LCSS, lung cancer specific survival; SBRT, stereotactic body radiotherapy.