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. 2022 Jul 6;136(13):1053–1069. doi: 10.1042/CS20220082

Figure 6. Intragastric administration of L-Gln can delay the development of OA in rats.

Figure 6

(A) The medial and lateral femoral condyle and tibial plateau of rats. (B) H&E staining. (C) Safranin-O/Fast Green staining. (D–F) Immunohistochemical staining of MMP-13, Aggrecan, and Collagen II. (H–J) Quantification with Image-Pro6.0; scale bar = 50 μm. (G) OARSI score. (K, L) The serum levels of IL-1β and L-Gln. #P<0.05 versus the control group. *P<0.05, **P<0.01 versus the OA group; Control: n=3, OA: n=4, OA+L-Gln: n=5.