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. Author manuscript; available in PMC: 2022 Jul 8.
Published in final edited form as: Toxicol Appl Pharmacol. 2021 Dec 18;438:115830. doi: 10.1016/j.taap.2021.115830

Figure 1:

Figure 1:

Simplified metabolic pathway of dibenzo[def,p]chrysene (DBC). Solid arrows indicate the primary metabolic pathway that is modeled in our physiologically based pharmacokinetic (PBPK) model, whereas dashed arrows indicate other secondary pathways that are not accounted for in our PBPK model. Compound names with asterisks are the chemical species that are explicitly modeled in our PBPK model.