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. Author manuscript; available in PMC: 2022 Jul 8.
Published in final edited form as: Toxicol Appl Pharmacol. 2021 Dec 18;438:115830. doi: 10.1016/j.taap.2021.115830

Figure 5:

Figure 5:

Measured concentrations of dibenzo[def,p]chrysene (DBC) and DBC metabolites in plasma (A -D) and urine (E - H), for two human volunteers: Volunteer 8 (left panel), and Volunteer 9 (right panel), orally administered with an oral dose of 29 ng of DBC. Lines are physiologically based pharmacokinetic (PBPK) model simulations of data.