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. Author manuscript; available in PMC: 2022 Jul 8.
Published in final edited form as: Toxicol Appl Pharmacol. 2021 Dec 18;438:115830. doi: 10.1016/j.taap.2021.115830

Table 4:

Organ-specific weights for humans expressed in terms of physiological measurements of body weight, height, and age ((40), unless noted otherwise)

Organ Male Female
Blood (13.1*H + 18.05*W – 480)/572.3 (35.5*H + 2.27*W – 3382)/617.8
Fat (1.20*BMI + 0.23*A – 16.2)*W/0.923/100 (1.20*BMI + 0.23*A – 5.4)*BW/0.923/100
Muscle FFM*54/100/1.04 FFM*48.9/100/1.04
Skin* 3300/1.04/1000 2300/1.04/1000
Liver 1.0728*SA – 0.3457 1.0728*SA – 0.3457
Heart (155.18*((H0.725)*(W0.425)*71.84/10000)1.29)/1.04/1000 (124.13*((H0.7763)*(W0.4081)*71.84/10000)1.242)/1.04/1000
Spleen 6.516*BW0.797/1.04/1000 6.516*BW0.797/1.04/1000
Kidneys (5.04 + 2.53*A + 1.31*W + 1.36*H – 255.7)*2/1000 (5.04*2 + 2.53*A + 1.31*W + 1.36*H – 255.7)*2/1000
Brain** 1.2875 1.1585
Lungs 0.021*FFM/1.04 0.019*FFM/1.04
GI 0.021*FFM/1.04 0.027*FFM/1.04
Pancreas 0.0017*FFM/1.04 0.002*FFM/1.04
Thyroid 0.00034*FFM/1.04 0.00043*FFM/1.04
Others^ 1453.03/1.04/1000 1524.88/1.04/1000

H = Height in cm; W = Weight in kg; A = Age in years; BMI = Body Mass Index in kg/m2

FFM = W – Fat mass = Fat Free Mass in kg; SA = W0.5378 *H0.3964*0.024265 = Surface Area in m2

*

Ref (42). Tissue density of 1.04 kg/L assumed

**

Estimated as the mean of White and African American populations (40)

^

Based on the sum of (gender-specific) all remaining rapidly-perfused organs (40)