. Author manuscript; available in PMC: 2022 Jul 8.

Published in final edited form as: Toxicol Appl Pharmacol. 2021 Dec 18;438:115830. doi: 10.1016/j.taap.2021.115830

Table 7:

Biochemical parameters (all first order rate constants with units 1/min) for mice and humans used in PBPK model

Parameter	Symbol^{^}	Mouse	Human
Absorption rate from stomach to liver	KAS	0.001^†	0.0001
Absorption rate from intestines to liver	KAI	0.008^†	0.1
Gastric emptying rate	KSI	0.01	0.02

^{^}

^†

Ref (26)