Table 2.

Intraoperative Variables

Variables	Lactate ≤ 1.5 mEq/l (N = 622)	Lactate > 1.5 mEq/l (N = 319)	P-value
Anaesthesia duration ( min)	347 [254–450]	372 [287–472]	0.001
Surgery duration (min)	262 [180–360]	289 [209–381]	0.002
Total crystalloid (ml)	2000 [1200–3000]	2400 [1500–3500]	< 0.001
Total colloid (ml)b	500 [500–1000]	1000 [500–1500]	< 0.001
Total blood product (ml)	498 [261–580]	540 [288–1475]	0.009
Total IN (ml)	2500 [1500–3500]	3000 [2000–4500]	< 0.001
Estimated blood loss (ml)	400 [200–900]	700 [300–1500]	< 0.001
Diuresis (ml)	300 [150–500]	300 [150–510]	0.258
Total out (ml)	870 [500–1400]	1110 [680–2000]	< 0.001
Net fluid balance (ml)	1505 [788–2350]	1750 [1000–2800]	< 0.001
Use of vasopressors, N (%)a	484 (77.9%)	269 (84.3%)	0.02
Lactate beginning of surgery (mEq/L)	0.7 [0.6–0.9]	0.9 [0.7–1.2]	< 0.001
RER beginning of surgery	0.80 [0.67–0.80]	0.80 [0.71–0.83]	< 0.001
Lactate end of surgery (mEq/L)	0.9 [0.7–1.1]	2.3 [1.8–3.0]	< 0.001
RER end of surgery	0.80 [0.67–0.80]	0.83 [0.80–1.0]	< 0.001

Values are presented as medians [interquartiles ranges] or numbers (percentages %)

^ause of any vasopressor (ephedrine, phenylephrine, noradrenaline)

^btotal colloid included 3% gelatin and 6% tetrastarch