Table 1.
Relationship between PRDM5 expression and clinicopathological characteristics in Discovery Data Set
| PRDM5 LOW | PRDM5 HIGH | P-value | |
|---|---|---|---|
| Patient characteristics | N = 109 | N = 45 | |
| Sex | 0.872 | ||
| female | 28 | 11 | |
| male | 81 | 34 | |
| Age | 0.864 | ||
| ≧60 | 79 | 32 | |
| < 60 | 30 | 13 | |
| Tumorinformation Location | 0.866 | ||
| Upper | 7 | 2 | |
| Middle | 50 | 20 | |
| Lower | 52 | 23 | |
| Tobacco | 0.812 | ||
| N0 | 89 | 36 | |
| YES | 20 | 9 | |
| Alcohol | 0.331 | ||
| N0 | 93 | 41 | |
| YES | 16 | 4 | |
| T stage | 0.105 | ||
| I-II | 38 | 22 | |
| III-IV | 71 | 23 | |
| N stage | 0.091 | ||
| N0 | 59 | 31 | |
| YES | 50 | 14 | |
| M stage | 0.360 | ||
| N0 | 107 | 45 | |
| YES | 2 | 0 | |
| TNM stage | 0.122 | ||
| I-II | 63 | 32 | |
| III-IV | 46 | 13 | |
| Histological grade | < 0.001 | ||
| Well | 3 | 7 | |
| Moderately | 65 | 35 | |
| Poorly | 41 | 3 | |
| Accompanying diseases | 0.933 | ||
| N0 | 89 | 37 | |
| YES | 20 | 8 | |
| Positive margin | |||
| N0 | 101 | 41 | 0.744 |
| YES | 8 | 4 | |
| Nerve invasion | 0.178 | ||
| N0 | 87 | 40 | |
| YES | 22 | 5 | |
| Vascular invasion | 0.013 | ||
| N0 | 83 | 42 | |
| YES | 26 | 3 |