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Correlation between AKT phosphorylation and CDR formation in Hep3B cells after growth factor stimulation. A and D Time course of signaling in response to EGF (160 nM) (A) and insulin (100 nM) (D). B and E Quantification of the pAKT/AKT ratio at the indicated times after EGF (B) or insulin (E) stimulations from three independent experiments. C and F The frequency of cells showing CDRs at the indicated times after EGF (C) or insulin (F) stimulations from three independent experiments
