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TCGA + GTEX data and hGAPDH activity. (a) Relative mRNA expression of genes regulating glycolysis pathway for normal human pancreas (N) and PDAC tissues (T), using TCGA and GTEx dataset (webtool GAPIA2). (b) Structures of the GAPDH inhibitors tested in this study. (c) Recombinant hGAPDH fractional activity upon incubation for 48 h at 37 °C with GAPDH inhibitors at 10 μM concentration. Statistical analysis * p < 0.05.
