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(a) Age-adjusted incidence rate (per 100,000); (b) age-adjusted mortality rate (per 100,000) of patients with hepatocellular carcinoma. Kaplan–Meier curves of patients with hepatocellular carcinoma: (c) Male vs. female patients (median OS for m and f, 9.5 and 6.8 months, respectively, p = 0.050); (d) comparison of OS with former time periods (median OS for 1990–1999, 2.6 months; 2000–2009, 5.6 months; 2010–2018, 9.3 months; p < 0.001).
