Figure 6.

Anticancer effects of cordycepin in other aggressive cancer cells. (A) ADA protein expression levels were measured by Western blot in retinoblastoma, AT/RT, and DIPG cell lines. (B–D) Cells were treated with for 5 days and then cell titer blue was used to measure viable cells. (E) Cells were treated with cordycepin for 2 days, and then cleaved PARP protein level was evaluated by Western blot. (F–I) Cells were treated with cordycepin and 1 µM of pentostatin for 5 days and then cell titer blue was used to measure viable cells. Values represent mean ± SD of experiments conducted in sextuplicate. *** p < 0.001, **** p < 0.0001 by one-way ANOVA analysis of variance compared with control group.