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The effects of high ratio of p53 isoforms to p53α/β on human cancer progression.
| Tumor Types | NAME of PROTEINS | Molecule Detected | Tumor Progression * | Reference |
|---|---|---|---|---|
| Breast cancer | ∆40p53:p53α | mRNA | ↑ | [152] |
| Colorectal cancer | ∆133p53:p53β | mRNA | ↑ | [69] |
| Cholangiocarcinoma | ∆133p53:p53α | mRNA | ↑ | [153] |
| Acute myeloid leukemia | p53β/γ:p53α | protein | ↓ | [154] |
* ↑ to accelerate tumor progression, ↓ to slow down tumor progression.
