CRC	Colorectal cancer
CTLA-4	Cytotoxic T-lymphocyte-associated protein 4
FoxP3	Forkhead box P3
ICs	Immune checkpoints
IDO1	Indoleamine 2,3-Dioxygenase 1
LAG-3	Lymphocyte-activation gene 3
NILs	Normal tissue-infiltrating lymphocytes
NT	Normal tissues
PBMC	Peripheral blood mononuclear cell
PD-1	Programmed cell death-1
DFS	Disease-free survival
TCGA	The Cancer Genome Atlas
TILs	Tumor-infiltrating lymphocytes
TIM-3	T-cell immunoglobulin and mucin domain-3
TME	Tumor microenvironment
Treg	T regulatory cell
TT	Tumor tissues