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. 2022 Jun 24;12:897676. doi: 10.3389/fonc.2022.897676

Table 1.

Patient’s Clinical information and MRI semantic features between non-metastasis and metastasis group in the training and external validation set.

Training set (N = 116) External validation set (N = 126)
Non-metastasis(N = 96) Metastasis(N = 20) P Non-metastasis (N = 107) Metastasis (N = 19) P
Age (years) (mean ± SD) 51.31 ± 18.851 48.10 ± 17.741 0.485 51.51 ± 17.159 49.74 ± 20.448 0.687
Gender Male 62 12 0.698 63 15 0.097
Female 34 8 44 4
T-stage 1 33 3 0.002 28 3 0.022
2 44 7 55 6
3 11 2 17 5
4 8 8 7 5
N-stage 0 86 15 0.161 98 14 0.022
1 10 5 9 5
MRI Semantic Features
Number Solitary 62 16 0.181 76 15 0.478
Multiple 34 4 31 4
Depth Deep 37 10 0.344 56 55 0.036
Superficial 59 10 51 14
Heterogeneous SI at T1WI <50% 62 8 0.041 53 9 0.862
≥50% 34 12 54 10
Heterogeneous SI at T2WI <50% 50 6 0.072 48 7 0.516
≥50% 46 14 59 12
Tumor volume of necrosis MRI signal 0 20 5 0.590 22 1 0.265
1%–50% 55 9 60 12
>50% of tumor volume 21 6 25 6
Peritumoral edema No 20 5 0.178 28 4 0.045
Limited 62 9 71 10
Extensive 14 6 8 5
Location Limb 93 19 0.648 61 9 0.202
Trunk wall 2 1 16 4
Head and neck 0 0 2 2
Internal trunk 1 0 28 4

SD, standard deviation; Calculated from student t-test or Mann–Whitney U test for ordinal variables and chi-square test or Fisher exact test for categorical variables, where appropriate.