AAD	age at first diagnosis
ACMG	American College of Medical Genetics
BC	breast cancer
CCG	Cologne Center for Genomics
CI	confidence interval
CNV	copy number variation
ER	estrogen receptor
ExAC	Exome Aggregation Consortium
FH	family history
GC-HBOC	German Consortium for Hereditary Breast and Ovarian Cancer
HER2	human epidermal growth factor receptor 2
IARC	International Agency for Research on Cancer
mBC	male breast cancer
MLPA	multiplex ligation-dependent probe amplification
NCCN	National Comprehensive Cancer Network
NFE	non-Finnish European
NGS	next-generation sequencing
PR	progesterone receptor
PTV	protein-truncating variant
PV	pathogenic variant
OC	ovarian cancer
OR	odds ratio
TCGA	The Cancer Genome Atlas
VUS	variant of uncertain significance