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. 2022 Jun 28;11(13):2049. doi: 10.3390/cells11132049
ALS amyotrophic lateral sclerosis
OS oxidative stress
MNs motor neurons
SOD1 superoxide dismutase 1
TDP-43 transgenic binding protein 43
FUS fused in sarcoma
MATR 3 matrin 3
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10
TBK1 tank-binding kinase 1
TUBA4A tubulin, alpha 4A
C21orf2 chromosome 21 open reading frame 2
C9orf72 chromosome 9 open reading frame 72
CCNF cyclin F
OXPHOS oxidative phosphorylation
ROS reactive oxygen species
NADH nicotinamide adenine dinucleotide
FADH2 reduced flavin adenine dinucleotide
ETC electron transport chain
IMM inner mitochondrial membrane
MCU mitochondrial calcium uniporter
OMM outer mitochondrial membrane
IMS inter membrane space
Grxs glutaredoxins
DPR dipeptide repeat
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
Fis1 mitochondrial fission protein 1
Mfn1 mitofusin 1
Drp1 dynamin-related protein 1
Opa1 optic atrophy 1
OPTN optineurin
LIR LC3-interacting region
SQSTM1 Sequestosome 1
H2S hydrogen sulfide
CAT catalase
PUFAs polyunsaturated fatty acids
mtDNA mitochondrial DNA
Nrf2 nuclear factor erythroid 2-related factor 2
ARE antioxidant response element
VDACs voltage-dependent anion-selective channel proteins
ER endoplasmic reticulum
AMPA α-amino-5-methyl-3-hydroxyisoxazolone-4-propionic acid
VAPB vesicle-associated membrane protein-associated proteins B and C
PTPIP51 protein tyrosine phosphatase-interacting protein 51
NMDA N-methyl-D-aspartic acid receptor
MANs mitochondria-associated endoplasmic reticulum membranes
TRPM7 transient receptor potential cation channel subfamily M member 7
hIGF-1 human insulin-like growth factor 1
PPARγ peroxisome-promoting life-activating receptor γ
TMP Tetramethylpyrazine nitric acid
MitoQ Mitoquinolmesylate
mPTP mitochondrial permeability transition pore
TSPO translocator protein
SHED-CM stem cells from human exfoliated deciduous teeth-conditioned medium