Figure 2.
mRNA expression and protein abundances of genes involved in proteasomal degradation; (a–h) the proteasomal subunits PSMA2, PSMB3, PSMB6, and PSMD and (i–l) the muscle-specific E3 ubiquitin ligases TRIM63 (encoding MuRF-1) and FBXO32 (encoding Atrogin-1) in skeletal muscle of patients with T2D (n =10–17) vs. obese controls (n = 10–19). Data are means ± SEM. * p < 0.05 and *** p < 0.001 vs. obese controls.