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. 2022 Jul 5;14(13):3287. doi: 10.3390/cancers14133287

Table 2.

Targeting BCSCs in Clinical Trials.

BCSCs Marker Agent/Intervention Study Phase Clinicaltrials.gov Identifier Study Status Type/Stage of Breast Cancer
CD44 Bivatuzumab Mertansine (CD44v6) I NCT02254005 Completed Breast Neoplasms
CD133 Other: Immunohistochemistry Staining Method N/A NCT04873154 Recruiting Breast Cancer
ALDH1 Other: Immunohistochemistry Staining Method and Laboratory Biomarker Analysis N/A NCT00949013 Completed Early-Stage Breast Cancer
Other: Immunohistochemistry Staining Method and Laboratory Biomarker Analysis N/A NCT01424865 Unknown Breast Cancer
Doxorubicin-Cyclophosphamide Regimen N/A NCT04581967 Recruiting Breast Cancer
EGFR/HER2 Trastuzumab N/A NCT01424865 Unknown Breast Cancer