Table 2.
Phthalate metabolite and ultraviolet filter concentrations [median (interquartile range)] (ng/mL) by pregnancy status, age category, and sex among participants in the Longitudinal Investigation on Fertility and Environment Study in Michigan and Texas (2005–2009).
| Total | <35 Years | ≥35 Years | ||||||
|---|---|---|---|---|---|---|---|---|
| Chemical (ng/mL) | %<LOQ | Total | Not Pregnant | Pregnant | Not Pregnant | Pregnant | Not Pregnant | Pregnant |
| Female partners | n = 403 | n = 122 | n = 281 | n = 94 | n = 247 | n = 28 | n = 34 | |
| mBzP | 4 | 3.7 (7.8) | 4.4 (8.3) | 3.4 (7.5) | 4.4 (7.9) | 3.5 (7.4) | 4.6 (8.3) | 2.9 (7.7) |
| mBP | 1 | 8.0 (14.5) | 9.2 (18.5) | 7.8 (14.1) | 8.8 (17.4) | 7.8 (14.1) | 11.6 (24.6) | 8.3 (12.8) |
| mCEPP | 2 | 14.7 (29.5) | 15.1 (38.1) | 14.7 (27.6) | 15.1 (33.8) | 14.7 (27.8) | 14.2 (43.5) | 13.2 (24.6) |
| mCMHP | 1 | 11.4 (25.5) | 11.9 (26.6) | 11.2 (22.8) | 11.5 (28.2) | 11.8 (21.9) | 13.1 (20.6) | 9.7 (26.8) |
| mCPP | 6 | 3.9 (8.7) | 3.6 (9.8) | 4.2 (7.5) | 3.6 (9.7) | 4.2 (7.4) | 3.7 (9.5) | 3.7 (8.1) |
| mEP | 2 | 68.7 (172.0) | 89.0 (213.9) | 61.7 (156.5) | 92.9 (187.9) | 62.2 (163.7) | 61.9 (264.7) | 60.0 (111.7) |
| mEHHP | 2 | 10.7 (20.9) | 10.7 (21.2) | 10.5 (20.5) | 11.3 (20.9) | 10.7 (20.3) | 7.0 (20.7) | 10.3 (24.8) |
| mEOHP | 4 | 6.0 (13.2) | 5.7 (12.3) | 6.0 (13.5) | 5.7 (11.0) | 6.1 (13.9) | 5.5 (19.9) | 5.4 (10.9) |
| mIBP | 4 | 4.0 (7.3) | 4.2 (9.1) | 3.9 (6.9) | 4.0 (8.9) | 4.0 (6.9) | 4.6 (10.4) | 2.1 (6.1) |
| BPA | 2 | 0.4 (0.8) | 0.5 (0.9) | 0.4 (0.7) | 0.5 (0.9) | 0.4 (0.6) | 0.4 (0.9) | 0.6 (1.5) |
| BP-1 | 1 | 2.5 (12.9) | 1.6 (8.4) | 2.8 (14.9) | 1.2 (6.9) | 2.8 (13.7) | 5.4 (27.7) | 3.3 (19.0) |
| BP-3 | 1 | 5.1 (29.0) | 3.6 (27.0) | 6.7 (31.8) | 2.4 (15.2) | 6.8 (30.3) | 13.3 (66.7) | 5.4 (43.9) |
| BP-2 | 28 | 0.05 (0.15) | 0.06 (0.18) | 0.05 (0.13) | 0.05 (0.15) | 0.05 (0.12) | 0.11 (0.2) | 0.02 (0.16) |
| 4OH-BP | 6 | 0.14 (0.25) | 0.14 (0.28) | 0.13 (0.24) | 0.14 (0.28) | 0.13 (0.24) | 0.16 (0.58) | 0.12 (0.22) |
| BP-8 | 29 | 0.11 (0.65) | 0.10 (0.3) | 0.12 (0.94) | 0.08 (0.26) | 0.12 (0.94) | 0.16 (0.79) | 0.07 (0.87) |
| Creatinine | – | 79.8 (103.0) | 88.4 (112.0) | 77.2 (99.9) | 90.1 (109.6) | 80.2 (99.7) | 82.3 (118.5) | 49.2 (72.0) |
| Male partners | n = 386 | n = 114 | n = 272 | n = 72 | n = 199 | n = 42 | n = 73 | |
| mBzP | 4 | 3.7 (7.1) | 4.1 (7.9) | 3.4 (6.9) | 4.8 (8.1) | 3.2 (7.0) | 3.3 (7.9) | 4.1 (6.7) |
| mBP | 1 | 7.5 (12.0) | 8.0 (17.3) | 7.1 (10.7) | 8.3 (15.7) | 6.8 (10.0) | 7.4 (18.6) | 8.9 (11.6) |
| mCEPP | 1 | 20.5 (37.7) | 22.5 (38.8) | 19.6 (37.5) | 22.5 (34.7) | 21.4 (37.6) | 22.4 (48.6) | 15.0 (36.0) |
| mCMHP | 0 | 18.6 (40.5) | 21.1 (40.5) | 17.2 (40.0) | 18.9 (38.6) | 19.5 (40.5) | 26.5 (41.2) | 15.9 (27.9) |
| mCPP | 3 | 5.6 (9.6) | 5.6 (9.0) | 5.7 (10.4) | 6.2 (8.3) | 5.6 (10.4) | 3.8 (9.0) | 5.7 (9.6) |
| mEHHP | 1 | 15.4 (33.0) | 16.9 (37.2) | 15 (29.9) | 16.9 (32.2) | 16.5 (30.5) | 17.4 (38) | 11.5 (24.6) |
| mEP | 1 | 97.2 (261.7) | 86.9 (239.1) | 102.1 (262.4) | 95.1 (256.7) | 98.6 (263.5) | 50.4 (232.5) | 111.7 (250.9) |
| mEOHP | 2 | 7 (15.2) | 7.7 (16.7) | 6.8 (14.5) | 7.7 (14.8) | 6.9 (16.2) | 8.2 (19.1) | 6.1 (10.6) |
| mIBP | 2 | 4.5 (7.3) | 4.8 (7.6) | 4.4 (7.1) | 4.5 (7.1) | 4.3 (7.2) | 5.1 (8.0) | 5.4 (6.5) |
| BPA | 2 | 0.5 (0.9) | 0.4 (0.8) | 0.6 (0.9) | 0.4 (0.7) | 0.6 (0.9) | 0.4 (0.9) | 0.6 (1.3) |
| BP-1 | 1 | 1.3 (8.0) | 0.6 (2.3) | 1.9 (9.9) | 0.6 (2.0) | 2.2 (10.0) | 0.7 (3.6) | 1.3 (9.5) |
| BP-3 | 2 | 3.0 (16.2) | 1.7 (5.2) | 4.0 (21.5) | 1.9 (4.4) | 4.1 (24.6) | 1.4 (5.8) | 3.9 (16.0) |
| BP-2 | 28 | 0.05 (0.12) | 0.05 (0.15) | 0.05 (0.11) | 0.05 (0.11) | 0.05 (0.11) | 0.03 (0.28) | 0.03 (0.13) |
| 4OH-BP | 4 | 0.14 (0.25) | 0.13 (0.28) | 0.14 (0.24) | 0.11 (0.26) | 0.15 (0.25) | 0.14 (0.28) | 0.13 (0.24) |
| BP-8 | 27 | 0.08 (0.44) | 0.05 (0.23) | 0.09 (0.75) | 0.04 (0.25) | 0.11 (0.58) | 0.07 (0.17) | 0.07 (0.91) |
| Creatinine | – | 139.8 (129.9) | 115.2 (139.5) | 145.4 (126.7) | 114.4 (143.3) | 146.4 (120.5) | 133.9 (96.4) | 140 (123.9) |
NOTE: monobenzyl phthalate (mBZP), mono-n-butyl phthalate (mBP), mono(2-ethyl-5-carboxylpentyl) phthalate (mCEPP), mono-[(2-carboxymethyl)hexyl] phthalate (mCMHP), mono(3-carboxypropyl) phthalate (mCPP), monoethyl phthalate(mEP), mono(2-ethyl-5-hydroxyhexyl) phthalate (mEHHP), mono(2-ethyl-5-oxohexyl) phthalate (mEOHP), mono(2-isobutyl phthalate (miBP), bisphenol A (BPA), 4-hydroxybenzophenone (4OH-BP), benzophenone 1 (BP-1), benzophenone 2 (BP-2), benzophenone 3 (BP-3), benzophenone 8 (BP-8).