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. 2022 Jun 28;11(13):2055. doi: 10.3390/cells11132055

Figure 2.

Figure 2

The regulation of ATII cell proliferation and differentiation. WNT/β-catenin, TGF-β, and NOTCH pathways dynamically regulate ATII cell proliferation and differentiation into ATI cells, although there are still many unknowns during the transitional state. Other transcription factors, growth factors, and signaling molecules are also involved.