Table 1.

Occurrence of selected NSAIDs in surface water, wastewater and drinking/underground water in different locations.

Surface Water (ng/L)	Reference	Wastewater (Effluents (E)/Influents (I)) (ng/L)	Reference	Drinking Water (DW)/Underground Water (UW) (ng/L)	Reference	Area
Ibuprofen
<0.3–56.0 3730.1 222.0 2.2 0.0−346.0 21.0–2796.0 0.9−115.8   0.1−0.6 524.0−17,600.0	[42] [43] [44] [45] [46] [47] [48]   [49] [50]	31,250.0 0−4926.0 (I)   20,130.0 0−10,600.0 (E)     0.2−1.9	[43] [44]   [46] [51]     [49]	223.6 (UW)/599.0 (DW) ND−1.2   92 5850.0 <LOD−17.2 7.0−836.7	[43] [51]     [51] [52] [53]	UK Poland Portugal Sweden Serbia North America China Taiwan Vietnam South Africa
Diclofenac
<0.5–261.0 5401.5 241.0 1.7−3.6 0−324 17.0–42.0 ND−1.5   0.3−0.4 1010.0−10,200.0	[42] [43] [54] [45] [46] [47] [48]   [49] [50]	40,570.2 0–269.0 (I)   1338.0     286.0 0.1−1.0	[43] [44]   [46]     [55] [49]	2770.0 (GW)/114.3 (DW)         <LOD−2.4 2.1−33.2	[43]         [52] [53]	UK Poland Portugal Sweden Serbia North America China Taiwan Vietnam South Africa
Naproxen
<0.3–55.0 1091.9 178.0 0.2 0−74.2 22.0 3.5   0.1−0.4 59,300.0	[42] [43] [54] [45] [46] [47] [56]   [49] [50]	551,960.0 8.8−1617.0 (I)   208.0 23,210.0 (I)   470.0 0.1−0.6	[43] [44]   [46]     [57] [55] [49]	21.0 (GW)/13.0 (DW)      27.6  44.0  <LOD−3.1  128.0	[43]     [46] [58] [52] [53]	UK Poland Portugal Sweden Serbia North America China Taiwan Vietnam South Africa
Ketoprofen
<0.5–4.0 132.2 0.3−89.0 0.3−1.3 1.4−54.5 509 <0.5−0.5 443.0−9220.0	[42] [43] [54] [45] [59] [60] [49] [50]	233,630.0 289.0−589.0 (I)   247.0   0.1−1.6	[43] [44]  [46]   [49]	731.8 (GW)/166.9 (DW) 0.09   16.0 (DW) 4.1 (GW) ND	[43] [61] [46]   [62] [63]	UK Poland Portugal Sweden Serbia China Vietnam South Africa

<LOD = below limit of detection; ND = non detected.