Table 3.
Prenatal urinary organophosphorus-pesticide metabolite concentration distribution in a nested case–cohort study of preschool attention-deficit hyperactivity disorder in the Norwegian Mother and Child Cohort (MoBa), birth years 2004–2008.
| OP metabolite | Population | N | LOQ | %>LOQ | Min | 25% | 50% | 75% | Max |
|---|---|---|---|---|---|---|---|---|---|
| DEP (ng/mL) | Case | 259 | 1.089 | 67.3 | <LOQ | <LOQ | 1.67 | 3.27 | 32.8 |
| Sub-cohort | 548 | 1.089 | 67.4 | <LOQ | <LOQ | 1.68 | 3.49 | 25.9 | |
| DETP (ng/mL) | Case | 259 | 0.594 | 41.5 | <LOQ | <LOQ | <LOQ | 1.37 | 25.0 |
| Sub-cohort | 548 | 0.594 | 47.4 | <LOQ | <LOQ | <LOQ | 1.58 | 131 | |
| DEDTP (ng/mL) | Case | 259 | 0.594 | 0.38 | <LOQ | <LOQ | <LOQ | <LOQ | <LOQ |
| Sub-cohort | 548 | 0.594 | 0.18 | <LOQ | <LOQ | <LOQ | <LOQ | <LOQ | |
| Sum DEP * (nmol/L) | Case | 259 | NA | NA | 2.04 | 10.1 | 18.2 | 34.3 | 241 |
| Sub-cohort | 547 | NA | NA | 0.02 | 11.5 | 19.7 | 37.3 | 581 | |
| DMP (ng/mL) | Case | 259 | 3.003 | 47.7 | <LOQ | <LOQ | <LOQ | 7.01 | 91.8 |
| Sub-cohort | 547 | 3.003 | 52.3 | <LOQ | <LOQ | 3.27 | 10.2 | 168 | |
| DMTP (ng/mL) | Case | 259 | 0.429 | 89.6 | <LOQ | 0.91 | 2.09 | 5.18 | 68.6 |
| Sub-cohort | 548 | 0.429 | 93.3 | <LOQ | 1.05 | 2.58 | 8.06 | 221 | |
| DMDTP (ng/mL) | Case | 259 | 1.320 | 13.5 | <LOQ | <LOQ | <LOQ | <LOQ | 37.6 |
| Sub-cohort | 548 | 1.320 | 16.9 | <LOQ | <LOQ | <LOQ | <LOQ | 83.9 | |
| Sum DMP * (nmol/L) | Case | 259 | NA | NA | 3.14 | 25.6 | 56.7 | 114 | 1363 |
| Sub-cohort | 547 | NA | NA | 0.05 | 31.7 | 66.1 | 156 | 1979 |
Note: DEP, diethylphosphate; DETP, diethylthiophosphate; DEDTP, diethyldithiophosphate; DMP, dimethyphosphate; DMTP, dimethylthiophosphate; DMDTP, dimethyldithiophosphate. * Values for concentrations below the LOQ were imputed. Values standardized to the geometric mean of specific gravity.