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. 2022 Jun 27;23(13):7117. doi: 10.3390/ijms23137117

Figure 2.

Figure 2

Exposure of astrocytes to sera of NMO patients increased BID expression. (a) The expression of BID increased significantly in human astrocytes cultured with sera of NMO patients (131.4 ± 9.3, n = 4) compared to astrocytes cultured with sera of HCs (73.7 ± 8.0, n = 4), as was determined with NanoString nCounter technology, (b) The expression of BID increased significantly in mouse astrocytes cultured with sera of NMO patients (1.02 ± 0.6, n = 18) compared to the HCs (0.54 ± 0.22, n = 15), as was determined using rt-QPCR. Each assay was repeated independently at least three times. Significance was determined by unpaired two-tailed student’s t-test (p ** ≤ 0.01, **** ≤ 0.0001). Error bars in all graphs represent standard deviation.